I've been experimenting with the Minotaur quite a lot lately and it certainly can be used to good effect.
Minotaur fish
The standard arc for the Minotaur can overlap solidly with L.Carro, Flamer, Banshee, Mines and Artemis. Using the light carronade makes it into a somewhat unusual blenderfish with superior arcs and maneuvering but difficulty getting kills. A gunner should really be used on this to exploit the ridiculous arcs with stamina. It often requires ramming to assist in breaking the balloon and to finish off the grounded enemy. With a bit of practice and crew co-ordination it might be possible to position above them using a banshee to keep the balloon down while the Minotaur pushes them into the ground.
Ive had some success with this outside of stacked games but it probably does require a superior crew and pilot to be of much use.
Minotaur galleon
My current attempt is lumberjack-Minotaur-l.flak. It is somewhat limited by the need for a good light flak gunner, a good lochnagar lumberjack gunner and a good Minotaur gunner which is not an easy crew to find. When it works however the Minotaur keeps them outside of the lumberjacks arming time and disrupts outflanking and once they drop below you the Minotaur accelerates them downward. If you get all 3 guns on them when grounded they will die very fast. Success has however been limited by the crew requirements and my own mediocrity as a galleon pilot.
I've also been gunner a number of times on a double Minotaur-L.flak/banshee galleon. It can be a very hard ship to attack and can kill reasonably well, it is however utterly useless on large open maps because the target gets pushed out of effective range almost immediately.
Minotaur spire
Possibly related to my being far better at spire than fish or galleon this has been my most successful experiment.
The loadout and crew roles i use are a little odd but have proved highly effective so far:
Top left - Hades
Top right - Artemis
Bottom left - Light Flak
Center - Minotaur
A main engineer with burst mans the Artemis and repairs the hull and main engine
A gunner or buff engineer mans the Hades and exclusively fires it.
A main engineer with heavy clip mans the Minotaur and Light Flak (leaving normal rounds in the Flak) and repairs balloon and lower engines
This solves a number of the problems with the spire and the particular guns on it.
-A mercury clip into the main gun on some spire builds will disable the 2 main guns, the gunner has lost their gun and the top engineer will leave theirs to repair the hull. In this case you lose the artemis to hull repair and while the lower deck engineer has the option of rebuilding the Minotaur or firing Flak as the situation demands, the hades can continue firing full time.
-The Minotaur does a good job of keeping the target outside of Hades and Light Flak arming time.
-Avoiding having the primary gunner focus on the Minotaur prevents your main firepower from being nullified by effective kerosene use.
-The pressure from the hades makes it harder to counter the Minotaur with kerosene.
It is from my experience so far a completely effective build and having significant killing power avoids the severe annoyance that Minotaurs can cause when you push someone around but cant kill them. I have yet to test it against squid or Hades/Merc - Art-Art mobula which will be likely the most challenging opponents.